Ì첩ÌåÓý

In the journals

A prescription cream called 5-fluorouracil (5-FU, sold as Adrucil and other brands) may help people reduce their risk for squamous cell carcinoma (SCC), according to a study published in the Jan. 3, 2017, JAMA Dermatology. SCC, the second most common cancer in the United States, strikes twice as many men as women.

Researchers recruited 932 people, 98% of whom were men, with an average age of 71. Each had experienced at least two skin cancers � SCC, basal cell carcinoma (BCC, the most common skin cancer), or both � on their face or ears within the past five years. They were randomly assigned to receive either the 5-FU cream or a placebo cream. Everyone applied a thin layer twice a day to their face and ears for up to four weeks. Over the course of a year, the 5-FU group had a 75% lower incidence of SCC compared with the placebo group. They also had a 11% lower incidence of BCC, but this difference was not statistically significant. It's not known why 5-FU helped prevent SCC but not BCC, according to the researchers.

Many people are bothered by double chins and try to conceal them behind turtleneck shirts and scarves. However, recent advancements have expanded the options for jowl removal beyond surgery to in-office treatments.

Cryolipolysis (Cool Mini)

This procedure, also known as "cool sculpting," treats a double chin. The clinician places a handpiece under the chin and chills fat cells there almost to the point of freezing, damaging their membranes so they are absorbed and metabolized by the body. The treatment itself takes about an hour, and results are seen over the subsequent two months. The procedure is usually effective and can be performed more than once. It can also be used to reduce love handles on the waist. The cost is approximately $1,000 per treatment.

Symptoms of dry skin, eczema, contact dermatitis, and psoriasis can overlap.

ÌýImage: © Sasha_Suzi/Thinkstock

It's easy to overlook dry skin during the winter, when indoor heating and dry air pull moisture from the skin. But sometimes it's tough to tell if dry skin is a consequence of the season or a sign of a serious condition. "I see a fair number of people who come in with psoriasis or eczema and had just assumed it was dry skin," says Dr. Jason Frangos, a dermatologist at Harvard-affiliated Brigham and Women's Hospital.

Why does skin dry out?

It's not just winter conditions that lead to dry skin; it's also a change in our skin's top layer, or epidermis. This layer is normally thick with naturally occurring fats and oils that act as a barrier to help retain moisture and prevent irritants from entering the skin.

Try these simple strategies to keep dry, cracking skin at bay during the cold weather.

Chapped, dry, cracked, and peeling... winter can be hard on your skin. What with the cold air and the lack of humidity, your skin spends the winter months fighting to retain moisture, not to mention fending off other insults from cold-weather staples like scratchy wool clothes and crackling wood fires.

How can your skin survive the season? We asked Dr. Barbara Gilchrest, senior lecturer on dermatology at Harvard Medical School, to weigh in with her best tips to help you protect your skin from winter dryness.

In the journals

ÌýImage: © Manuel-F-O/Thinkstock

While it's important to have any suspicious mole checked for possible skin cancer, a study published online Aug. 29, 2017, by the Journal of the American Academy of Dermatology suggests most melanomas � the deadliest skin cancer � appear as new spots on the skin. The researchers reviewed 38 studies involving 20,126 cases of melanoma and found that 29% of diagnosed melanomas came from an existing mole, while 71% appeared as new spots. Moreover, they discovered that melanomas that grew from moles were thinner and thus less aggressive than other melanomas. In fact, people whose melanoma was associated with a mole had a better prognosis than others.

The study's authors stressed the importance of looking for any new spots on the skin as well as checking moles for changes, like itching or bleeding, and to see a dermatologist if needed. The American Academy of Dermatology encourages everyone to perform regular skin self-exams, and to ask a partner to check hard-to-see areas like the back. You can learn how to do a skin self-exam, and much more, at .

Research we're watching

ÌýImage: © ChesiireCat/Thinkstock

To catch skin cancer early, be on the lookout for new spots on your skin. A recent study found that more often than not, melanoma occurs as a new spot on your body � not as changes in an existing mole. The study, published online August 29 by the Journal of the American Academy of Dermatology, found that only 29% of melanomas came from an existing mole on the body that changed. In 71% of cases, melanoma occurred in a new lesion that popped up in a new place on the skin. In addition, the study authors noted that melanomas that do occur in existing moles tend to be thinner than melanomas in new lesions.

In addition to looking for new and unusual spots on your skin, remember your ABCDs to spot the signs of melanoma:

Research we're watching

You probably know to have your skin checked frequently for the signs of melanoma. But you should also be looking out for another, more common type of skin cancer � squamous cell carcinoma. This potentially lethal skin cancer can show up on your skin as a white or pink bump, a non-healing sore, or even a scaly patch. According to the American Academy of Dermatology, cases of squamous cell carcinoma are on the rise, with some 700,000 new diagnoses each year.

"While other skin cancers may be more lethal, they're less common," writes Dr. M. Laurin Council, an assistant professor of dermatology at Washington University in St. Louis. "Squamous cell carcinoma is highly treatable when detected early, so it's important for people to know the signs of this disease and keep a close eye on their skin."

Ask the doctor

ÌýImage: © Boarding1Now/Thinkstock

Q. I'm confused about vitamin D. How much should I take?

A. There's considerable controversy as to whether most people should take a vitamin D supplement at all. Most of the vitamin D in our bodies is made by our skin, when it is exposed to sunlight. In contrast to most other vitamins, we don't get much vitamin D in our diet. Authorities recommend, however, that children from age 1, and adults through age 70, take 600 international units (IU) daily, and that adults 71 years and older take 800 IU daily. People with, or at risk for, certain bone diseases need to take more than this amount. There's general agreement that doses above 4,000 IU daily can be toxic to adults, with lower doses toxic to kids.