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A condition caused by spontaneous genetic mutations in bone marrow cells, known as clonal hematopoiesis of indeterminate significance (CHIP), is linked to an increased risk of cardiovascular disease. Some of these mutations are clearly related to inflammation, a well-known contributor to the buildup of fatty plaque inside arteries. Experts hope that future research on CHIP will eventually lead to genetically directed therapies to address the condition.

Playing pickleball can boost cardiovascular health, but this popular sport can leave older players prone to injuries. Preventive strategies including taking a class to learn proper form; choosing supportive gear such as well-fitting shoes and sleeve braces; warming up before playing with squats, lunges, and heel raises; and doing lower-body strength-building exercises a couple of times per week.

People with type 2 diabetes may have greater protection from cardiovascular problems if they keep their systolic blood pressure (the first number in a reading) to 120 mm Hg or lower, according to a 2024 study.

A 2024 study found that people who follow a diet with a higher ratio of plant-based protein to animal-based protein may have a lower risk for cardiovascular disease and coronary artery disease compared with individuals who eat a lower plant-to-animal protein ratio.

In a large 2024 study, people who ate more plant-based proteins than animal proteins had the lowest risks of developing cardiovascular disease and coronary heart disease, compared with those who ate more animal proteins than plant-based proteins.

Having type 2 diabetes doubles a person's odds of heart disease, and this risk may be present as early as 30 years prior to the diabetes diagnosis, according to a 2024 study. The findings support the long-held observation of the shared underlying causes of diabetes and heart disease. These include factors that contribute to both conditions, especially the tendency to accumulate fat in the middle of the body, known as abdominal obesity. This problem tends to occur in tandem with high blood pressure, unhealthy lipid levels, and elevated blood sugar—a cluster of signs and symptoms called metabolic syndrome.

High levels of Lp(a)—a fatty particle similar to LDL cholesterol—may double or triple a person's risk of a heart attack. About one in five adults may have elevated levels, which also raises the risk of stroke and aortic stenosis. Unlike LDL, which rises with age and is influenced by diet and exercise, Lp(a) remains largely constant over a person's lifetime, so a one-time test suffices for screening. Lp(a) testing is becoming more common now that five promising new Lp(a) therapies are in development.

Social media sources may share misleading information about canola, soybean, and other seed oils. But these oils, which consist mostly of unsaturated fat, can be a good source of heart-healthy fat when combined with whole, fresh foods rather than in processed foods like crunchy, salty, or sweet snack foods. Consuming unsaturated fat in place of saturated fat (found mainly in animal-based foods) is linked to a lower risk of heart attack and death from heart disease.

After a heart attack or stent placement, people typically take a combination of aspirin and another antiplatelet drug. After one year, the new standard practice is to stop the aspirin, in contrast to the previous practice of stopping the other drug.

A 2024 study involving more than 72,000 healthy people ages 40 to 79 found that those whose sleep and wake times fluctuated most had a 26% higher risk of having a heart attack, stroke, or similar problem, compared with those whose sleep patterns fluctuated least.