Boosting share of protein from plants in diet may lower heart disease risk
In the journals
- Reviewed by Howard E. LeWine, MD, Chief Medical Editor, Ì첩ÌåÓý Publishing; Editorial Advisory Board Member, Ì첩ÌåÓý Publishing
An observational study suggests that increasing the proportion of plant-based protein in the diet may reduce the risk of cardiovascular disease and coronary artery disease. The study results were published in the December 2024 issue of The American Journal of Clinical Nutrition. Researchers used data on diet, lifestyle, and heart health collected over 30 years from nearly 203,000 men and women. Participants reported their dietary intake every four years.
The researchers calculated each participant's total protein intake, measured in grams per day, and their specific intakes of animal and plant proteins. Poultry, red meat, and dairy were the top contributors to animal protein. The main plant protein sources were refined grains, whole grains, potatoes, nuts, and beans. Participants whose diets had the highest proportion of plant versus animal protein had a 19% lower risk of cardiovascular disease and a 27% lower risk of coronary artery disease than those who consumed the lowest proportion. According to the researchers, the average American eats a 1:3 plant-to-animal protein ratio (meaning one serving of plant protein for every three servings of animal protein).
The findings suggest a dietary ratio of 1:2 plant to animal protein is more effective in preventing cardiovascular disease, and a ratio closer to 1:1 is best for preventing coronary artery disease. However, the ratios are estimates and further studies are needed to determine the optimal balance between plant and animal protein intake.
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About the Author

Matthew Solan, Executive Editor, Harvard Men's Health Watch
About the Reviewer

Howard E. LeWine, MD, Chief Medical Editor, Ì첩ÌåÓý Publishing; Editorial Advisory Board Member, Ì첩ÌåÓý Publishing
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