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Most people will experience shoulder pain at some point in their lives. The most common causes of shoulder pain are bursitis, rotator cuff problems, frozen shoulder, and osteoarthritis. They can occur for various reasons, such as overuse, injury, and age-related wear and tear. A doctor may be able to make a likely diagnosis based on a person's symptoms, a shoulder exam, and sometimes MRI. Treatment often includes a combination of rest, over-the-counter medication, corticosteroid injections, and physical therapy. In some cases, surgery is needed to repair damage.

Chronic pain sometimes originates in the pain-sensing nerves as well as injured body tissues.

Many medications claim to relieve migraine pain, but some are more helpful than others. In a large study looking at real-world data on 25 drugs, migraine sufferers rated the most and least helpful options.

Several types of "electroceutical" therapies use tiny zaps of electricity to help ease chronic pain. Transcutaneous electrical nerve stimulation (TENS) therapy and electroacupuncture are designed to work by interrupting pain signals being sent to the brain. Scrambler therapy is thought to work by changing pain information sent to the brain. Good candidates for such therapies are people with arthritis, neuropathy, neck or back pain, or pain from cancer treatment. Some people should stay away from electroceuticals, including those with any kind of implanted stimulation device, such as a pacemaker or bladder stimulator.

A pulled muscle sometimes feels similar to a pinched nerve. But muscle pain is usually dull and doesn't radiate outward, while pinched nerve pain is sharp and burning and extends from one area to another. Pinched nerves can stem from pregnancy, arthritis, or injuries.

Most cases of chest pain don't signal heart problems. While chest discomfort of any kind should never be ignored, many conditions can trigger it. These include gastroesophageal reflux disease, gallstones, asthma, ulcers, anxiety, COVID, esophagus spasms, costochondritis, pulmonary embolism, pleurisy, aortic dissection, and pericarditis. Chest pain is likely to be unrelated to the heart if it's brief, triggered by eating, doesn't worsen with exercise, occurs only with movement, coughing, or breathing deeply, or it's localized to one spot.

Most acute back pain happens because of weak muscles related to aging and inactivity. Symptoms usually last a few days, but pain and stiffness sometimes linger for a couple of weeks or longer. Frequent episodes can make people less active, as they are fearful about straining their back. Managing acute back pain is a two-step approach. First, treat the pain with over-the-counter remedies, cold and heat therapy, and rest, and then strengthen the back muscles and improve flexibility to prevent recurrent back pain episodes.