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A groundbreaking blood test might someday identify cancer in people with unexplained but worrisome symptoms like unexplained weight loss, frequent fatigue, constant nausea, and new pain.

It's common to have a cough for weeks after an upper respiratory infection. When a cough lasts six weeks or longer, doctors may order a chest x-ray to check for an underlying lung problem. Chronic coughing also can result from medications, postnasal drip, acid reflux, or asthma.

Cardiopulmonary exercise testing (CPET) can help diagnose unusual causes of breathlessness, such as pulmonary hypertension or heart failure with preserved ejection fraction. CPET collects information about a person's heart and lung function to assess how the body responds to exercise. It may also help doctors better understand the lingering fatigue and breathlessness that sometimes occur after a COVID-19 infection.

Platelet-rich plasma injections are used to reduce pain and speed healing for a number of common problems that affect the tendons, muscles, and joints, ranging from arthritis to shoulder pain. But a growing body of research shows that they may not be effective for some conditions, including knee osteoarthritis, ankle osteoarthritis, and Achilles tendinitis. There is some evidence that it may be effective for lateral epicondylitis (tennis elbow). People should consider whether there is a better option before undergoing PRP injections.

The FDA recently moved to help make certain that women considering breast implants have a clear picture of what implants involve before moving ahead with surgery. The agency announced a series of changes in October 2021. These include new labeling requirements for breast implant manufacturers, a requirement that facilities provide patients with a checklist outlining potential risks and benefits related to breast implants, and updated screening recommendations to detect leaks in silicone breast implants.

Most people don't benefit from colonoscopies after age 75, but before stopping they should have a discussion with their doctor.

A test called a coronary artery calcium (CAC) scan uses a special type of x-ray to look for plaque in the arteries of the heart, which raises the risk of heart-related problems. While CAC scans can be valuable for detecting people at higher risk of heart problems from plaque buildup, this test isn't right for everyone. It's typically most useful for people who don't yet have symptoms of heart disease, but who do have some risk factors. Determining how much plaque is in the arteries can help guide decision making about preventive strategies. The test is less useful for people at very low or very high risk for heart disease.

Men are less likely than women to get regular exams and tests, especially when they are younger. But as they age, routine screenings are essential. There are certain tests most men should have at some point, including ones for colon cancer, high blood pressure, hepatitis C, diabetes, and HIV. Other tests men should consider if they are at high risk for specific ailments, such as abdominal aortic aneurysm, hepatitis B, and lung cancer.

A substance that binds to blood clots may one day offer a novel, less invasive strategy for finding dangerous clots in the heart and elsewhere in the body.