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Research we're watching

A long-term study from researchers at Johns Hopkins University School of Medicine has found that men's hearts typically grow with age, while women's shrink. The researchers used magnetic resonance imaging (MRI) to study the left ventricle—the main pumping chamber of the heart—in around 3,000 men and women who were enrolled in the Multi-Ethnic Study of Atherosclerosis. All of the participants—who ranged in age from 54 to 94—were free of cardiovascular disease when they entered the study. They had heart scans at the start and 10 years later.

Comparing the MRI scans of men and women, the researchers found that both had declines in left ventricular volume (the amount of blood the chamber holds) over the decade. However, the mass of the ventricle itself increased in men, while it decreased slightly in women. And having a bigger heart seemed to be a disadvantage. It was associated with higher blood pressure and body mass index and lower levels of HDL (good) cholesterol. The study was published online October 20, 2015, by the journal Radiology.

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Here's another reason to take sweetened drinks out of your diet: a study published online Nov. 2, 2015, by the journal Heart suggests that drinking sweetened beverages each day is linked to an increased risk for heart failure in men. Heart failure is a gradual decline in the heart's ability to pump enough blood to meet the body's needs. Researchers tracked the dietary information of 42,000 middle-aged or older men in Sweden from 1998 to 2010. They made no distinction between types of drinks or how they were sweetened, whether it was with sugar, fructose, or artificial sweetener. However, coffee, tea, and fruit juice were not included in the study. After excluding potentially influential factors, researchers noted that men who drank at least two daily servings of sweetened drinks had a 23% heightened risk of developing heart failure compared with men who didn't drink sweetened beverages. The study didn't prove that sweetened drinks caused heart failure. In fact, the researchers pointed out that drinking a lot of sweetened beverages is usually an indication of a poor diet, which is a risk factor for heart failure in itself. But they also noted that sweetened drinks are associated with obesity and type 2 diabetes, which are risk factors for heart failure, too. Best advice: avoid sweetened beverages or at least limit them to occasional consumption.

These innovative devices and procedures for diagnosing and treating heart conditions are on the horizon.

For the most part, the Harvard Heart Letter focuses on treatments that are already available for people with heart disease. In this article, we're making an exception. Editor in Chief Dr. Deepak L. Bhatt selected five innovative technologies in the world of cardiovascular health that he predicts we'll be hearing more about in the coming years.

Ask the doctor

Q I have a relative who had a total cholesterol value of 155, yet he still had a heart attack with 90% blockage in one artery. How could that happen?

A I understand your confusion, considering how doctors have long focused on the importance of having an optimal total cholesterol level (less than 200 milligrams per deciliter or mg/dL) as a way to lower the chance of having a heart attack. It's actually the harmful LDL cholesterol value that's most important in terms of this risk. However, a person with a total cholesterol level of 155 mg/dL probably has an LDL level under 100 mg/dL, which is currently considered a reasonable target for avoiding heart disease.

Ask the doctor

Q. I take my blood pressure medication twice a day. Or at least I am supposed to, but I sometimes forget the second dose because my evenings tend to be really busy. What can I do?

A. One idea is to leave a sticky note on your bathroom mirror or near your bed as a reminder. Or try using an alarm (either a traditional alarm clock or one on a smartphone) that rings close to the time when you normally go to bed. You might also consider taking the second dose with dinner, assuming your doctor or pharmacist says it is okay to take your particular medicine with food.

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Clots in the lungs are twice as deadly as heart attacks.

If you scrape your leg, blood clots come to the rescue to heal the wound. But if a blood clot forms deep inside a leg vein, it's a different story. Known as a venous thrombosis—a term meaning "blood clot in a vein"—this type of clot can cause pain, swelling, and redness in the affected limb. When one forms in a leg or arm, it's called deep-vein thrombosis (DVT). But the real threat happens if the clot breaks off and travels to the lungs, causing a pulmonary embolism.

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New guidelines and a novel diabetes drug point to new treatment approaches.

When it comes to the cardiovascular dangers from diabetes, the statistics are pretty disheartening: about two-thirds of people with type 2 diabetes ultimately die from heart disease or a stroke. But there's progress afoot. Recently updated guidelines and a novel diabetes drug with proven heart benefits offer promise for making a dent in that dire statistic. And in a nod to the importance of early detection, the U.S. Preventive Services Task Force recently recommended that adults ages 40 to 70 who are overweight be screened for diabetes (see "Diabetes screening tests").

To use the online heart age calculator, the only numbers you need are your height, weight, and blood pressure reading.

Most Americans are not as young at heart as they might like to believe. More than three in four adults have a "heart age" that's greater than their chronological age, according to federal health officials.

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Research we're watching

Drinking as little as one sugar-sweetened beverage a day is linked to a slightly greater risk of high blood pressure, a new analysis suggests.

Researchers pooled findings from six studies that included a total of more than 240,000 people. They found a 12% higher risk of high blood pressure among people who drank one or more sugary drinks daily compared with those who drank none. Serving sizes of the beverages varied from 7 to 12 ounces among the different studies.

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Research we're watching

Women who have heart attacks before age 60 may be less likely to receive a lifesaving procedure to restore blood flow to the heart (an angioplasty plus a stent) than men in that age group, according to a study in the Oct. 26, 2015, Journal of the American College of Cardiology. (Stents are tiny mesh tubes that help keep arteries open.)

Data for the study came from a nationwide sample of more than 630,000 people ages 18 to 59 who had heart attacks. Younger women also were more likely to die in the hospital compared with younger men (4.5% versus 3%, respectively). However, men may be more likely to die before reaching the hospital than women, which may partly explain that difference, the researchers say.