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A buildup of fat inside the liver, known as nonalcoholic fatty liver disease (NAFLD) affects about 25% of adults. This under-recognized condition is closely linked to obesity (especially excess weight around the middle of the body), type 2 diabetes, and cardiovascular disease. People with NAFLD can slow or even reverse the condition with the same lifestyle strategies that improve cardiovascular health: losing weight, adopting a healthy diet, and exercising regularly.

Contrary to its reputation as an anti-aging supplement, human growth hormone is not effective at turning back the clock, and it may carry health risks. Commitment to a healthy diet and regular exercise is still the best formula for healthy aging.

Losing 5% of one's total body weight can result in clinically significant physiologic changes. For example, losing a little weight can reduce heartburn, knee pain, blood pressure, and diabetes risk. Losing 5% of one's body weight may also lead to better sexual function, more restorative sleep, extra energy, and more self-esteem. To reach a 5% reduction in total body weight, it helps to exercise; eat a healthy diet rich in lean proteins, whole grains, fruits, vegetables, legumes, nuts, and seeds; and get enough sleep.

The increase in obesity and type 2 diabetes among Americans has led to an increase in fatty liver disease. Weight loss and exercise are the mainstays of treatment.

For people who have risk factors for heart disease, it's important to make lifestyle changes like losing weight, getting more exercise, and eating a healthier diet. Longstanding habits are hard to change, but managing the challenge of healthy eating is easier if people have a partner who is supportive and involved in making food choices.

Diabetes is a condition in which both high and low glucose levels are harmful to the body. In older individuals with multiple risk factors for hypoglycemia, the goal should be the best blood sugar control that can be achieved without putting the individual at risk for dangerously low blood sugar.

Excessive drinking can contribute to high blood pressure, obesity, and stroke, while moderate drinking (no more than one drink per day for women and two drinks or fewer per day for men) is linked to a lower risk of heart problems. One possible mechanism might be stress reduction. Brain scans of people who reported light to moderate drinking show less activity in the part of the brain that responds to stress, compared with the scans of people who abstained or drank very little. Stress not only raises blood pressure and heart rate but also triggers inflammation that causes plaque buildup, which contributes to heart attacks.