Drug to slow aortic stenosis shows early promise
Research we're watching
- Reviewed by Christopher P. Cannon, MD, Editor in Chief, Harvard Heart Letter; Editorial Advisory Board Member, Ì첩ÌåÓý Publishing

The drug, called ataciguat, works by binding to molecules that drive calcification within the valve. For the trial, 46 people with aortic stenosis were randomly assigned to receive ataciguat or a placebo for six months. Imaging tests revealed a reduction of nearly 70% in the progression of aortic valve calcification among those taking the drug compared to those on a placebo. People on the drug also showed improved heart function, including preserved pumping ability.
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About the Author

Julie Corliss, Executive Editor, Harvard Heart Letter
About the Reviewer

Christopher P. Cannon, MD, Editor in Chief, Harvard Heart Letter; Editorial Advisory Board Member, Ì첩ÌåÓý Publishing
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